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What does dichloromethane solvent do in extraction? CAS No 75-09-2

Mar 19, 2026 Mesaj bırakın

Dichloromethane (DCM or methylene chloride) acts as a highly effective, volatile organic solvent in liquid-liquid extraction to dissolve and separate organic compounds from aqueous mixtures.

CAS No 75-09-2 DCM solvent is widely used in laboratories and industry due to its high extraction efficiency, low boiling point, and good phase separation behavior.


Density (20℃) 1.33 g/cm³
~40 ℃
~1.3 g/100 mL
High (~47 kPa)
0.44 mPa·s

 

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Dichloromethane (DCM) selectively dissolves a wide range of organic compounds, such as lipids, oils, fats, and alkaloids (including caffeine).

Dichloromethane is immiscible with water, thus forming a distinct, separate layer that facilitates the separation of the target extract from aqueous impurities.

High-Density Separation: Due to its higher density than water (approximately 1.33 g/cm³), dichloromethane settles to the bottom in a separatory funnel, simplifying extract collection.

With a boiling point of approximately 40℃, dichloromethane evaporates easily, leaving a purified extract, making it ideal for recovering heat-sensitive or volatile substances.

 

  • Decaffeine Extraction: Used for extracting caffeine from coffee beans and tea leaves.
  • Natural Product Separation: Used for separating active pharmaceutical ingredients and natural compounds.
  • Essential Oil Recovery: Used for separating and recovering essential oils from aqueous distillates and hydrosols.

 

 

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Dichloromethane (CAS No 75-09-2)

  1. Use in well-ventilated areas

 

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